Controlled environment glove, also known as Clean Room Gloves, materials must provide protection against particulate contamination. They are widely used in electronics and pharmaceutical industries. Critical environment gloves are typically Class M 3.5 (Class 100) and M 5.5 (Class 10,000) and higher. Controlled environment gloves are made from polyester, nitrile and nitrile/rubber combinations, natural rubber latex, polyvinyl chloride (PVC) and polyurethane.